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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be2636993a8416ce90a2d1df4b2f5d08f21c09a67a6e32254f261192ee0baa05' 
  AND token = 'E4JbVsBagKjy+JegpeUd1n40kGFhHoPhmN+3BEc9vUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00108

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}