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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a53315a997b6e6dd2245f4b8d5fe9e56aa628d633d846500311d554a625006e' 
  AND token = 'XAewD9OWqbOkLQ1ryTKAtTfn+qSmuH4OHTX/ZofBdPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00096

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}