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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ad45c02e879abaa36d30fe60fa46bc262eeff75016e840422c8a9cf1e127c6c' 
  AND token = 'K0bhca+iYnm89QMt7Ir4FHsRLyKmhmuoiRXu2SEJSVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00091

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}