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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b722da8e0446f10f61d0e93e04ad3b8159d37db34702eac79b158469d20b145' 
  AND token = '2GH/ut0MbDjctG4Pt7uEYePvLtjVhuTcLJTGJ9UqOzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00102

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}