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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d3d243e131cd287d75cb93723b09eb7c463533c8df31281f1a2251db35e10e' 
  AND token = 'Izkz5X/SCBoW2TOqEf1VYtVpgWFRQC0SQlEBOW84gU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00104

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}