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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7c4666413e56631735aeda8843b35d2b6bb173188c1f9244e43041ba42587ac' 
  AND token = '2ApFsyeXZ51G+2m0ZQwN+jER8TgCMvCuk93f/MyV8co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00131

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}