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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a10aeafe9cd851339d7c0bc24e5cc0463756d21c0d700fa70cf48b3c87b68c' 
  AND token = '+jsAy//W6tdg6auYUcJa+gq5d6edK/KlkgcGjC1tBvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}