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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9880539403e651fa76c333860d2e29edd5cd9f5b25e25c9117186e2a43fee451' 
  AND token = 'SaNZo0N72bqHxWFWw8MiXgl7xBkXoCSz2FBnjA9PjCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00117

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}