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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748b482d0e159895fe18699de905df48e527b9bd1343a50574b5e38c1a052631' 
  AND token = 'OqikZi2mFcF2GTj3CeP0cgjXDb2nLi5/yD0rt6jOI8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00099

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}