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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2be0be8759f2a18eaba1d33b2456be55a565c4daf8c11e2f5dfdce39c903f0a6' 
  AND token = 'cTMgD92BWsPGEIJ1z4odZeC2etyHKaLEqxaPN3sUrJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00102

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}