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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29bb3b32950fdd85c484a53b91a926e7b7c14e9a02940c79e0dfeccfccb028ec' 
  AND token = 'VFUpp1N+jQs1UNMMj0EACfetLsY9GGFh4KivbCrQ+YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00086

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}