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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27875d5fd2246af59b48b3838415ad6b09830cd480a230ddc84229916789c0d8' 
  AND token = 'u46USKur73VMOKLoKsjzUzh2eH01OXJwQprVzHwcOIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}