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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9de3a7f8557b3226bd1568c14e9d0e35dd12c3933155afc850f2322c6f376e6a' 
  AND token = 'Wk6enJ1Y532y6lQMnMqHhgc4iWxpOGkm9Y+WYSBzESU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00105

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}