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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e0d2a3ef19d61acb32dfabcd974473800490bc294db4f58e3baff94ec5fb604' 
  AND token = 'DDPLdsROV2vX4n3Z4fkFg+J9+HpQQo3hBfhe/ekf4nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}