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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec81a55ffa8b97753f3ad44f10bdca5638a8323d19f495d669756af55c72c449' 
  AND token = 'Ag7Z/91mw5IIOenn9adjbTkNoHSQMx2x/VC7PYuv8fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00114

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}