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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb527cb822301663a698ab86e5cf6a3dcec5ec9ae5c542579d2a6f922ab21701' 
  AND token = 'ML9CBpWw57YAyQeV/WvroZr8MvZHdzm6qsDZyqZcNBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00119

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}