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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1af9b0d2f6974af543711c1e4fcbddf9e68a338a1484d4213ca29710b2d737a' 
  AND token = 'HzDu2jjOvmEdeFI1CiSJuNlmUyRjxhH+Uug8fj8BsKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00102

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}