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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549cd6c61e728f5e315d2ea16fd53da43147c8eab32e720b64d9b60c36bed575' 
  AND token = 'fhDmwxb2hsxLTi4CWmvzX4+z8zwv3x7QBT0ETdP6c/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00125

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}