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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c777c5123df7b1b384c86bf3d852a97e516a1fdd5aff80eece8b818719c4234' 
  AND token = '2ftTl5o2OGCmWyt7I5felH+03wxlmjwMry7+HcTnCsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}