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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2000fd9c65cfd29a6d156b95da3381f75fe27007ef55cc0c1c6bac9b46cf5070' 
  AND token = 'L+Tp7S2rzYqCTURZkMOGayaf7dJJ2/AhZDgBsBLWv80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00103

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}