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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e293f6f8bb07e9d5b65e659a1bef4d5c9b3976049caa007f20bcdbd5d8a68da' 
  AND token = 'a/Z99LZHmDT9KV07c+zih4PhLlBbZRrRarvYz6f6zHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00120

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}