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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45cb873ccf8e3a41ff97faab04aa2780e0b493dd0bc2a3c1ae8e8c080478fe78' 
  AND token = '8/TL3PUARUgLW9S4dpP3j0vhg4g+KZmHM9niMKQhvyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00096

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}