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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180c5a109cf03b79c684444db029ea980d1a17c6f02c95e72ebe80f33722ef42' 
  AND token = '1wI/hyTsufCMNPPxTSnWz5uSt7z9qcmWO0RBj3o6db8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00096

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}