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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c41ded4cc11b8b7fa55a3f03e6aa262d976002f0eb90129bf29819faaf6e778' 
  AND token = 'lkO6N5fl9CCfD2dKgOKcxxvazLHSrTxkmP5l/NTYj5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00097

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}