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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50af295d7e5f8ed79ad82d4caae10dbfe096e6eb9f2d371517a22d546c86603' 
  AND token = 'z6/+Ij7wi98+3nLYiPc46omgedw2n/CqSK3s0ELm50M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00095

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}