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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d578b9a168843ee2111b7bef6516b37cc0f4fb77e9c902986e0258e2ea8aed8' 
  AND token = 'mPt2bjzjb9XdSsC5Aanev63sauYiaTUvSoGtQHc2F54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00095

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}