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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '378c1d8aaaec3399aad28c3aea8957d8106e993774a9118e5a1ed5739f5c97d3' 
  AND token = 'm+VFrCdr6BXuZPZyLgUir9+N8YxKrHQ9zNWjv6348Ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00109

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}