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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8640dc1abf7bcb8b3792e855dc1525d4f2b748506789d0c72582c38f1c8d58c' 
  AND token = 'NVN7ZkTbllP4rMoAtALb20Y16awK/XQ7qXU+M+EIs/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}