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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d9b257c67223046a3c7fb2d16fb8e5d550b0404ddfd13ddfdd0c49db475c8c4' 
  AND token = '7gupfBcw0dEIUAW4/p7qAixlhngs42+bYRM0YF9gstM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00095

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}