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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a37d656c6b4b18a955c6b4de42e737e4cb954731f453914ab7f009e6a45f7d' 
  AND token = 'no3OmB7NIB5T5Ir//y6vnDY2SRNMUQ2hhDjc3OWtPr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00123

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}