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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05132728495d77fb0430ae293f8b167d6751e86a06aec42439d18fbfd443df48' 
  AND token = 'MmBgn/UPCIv+bC89n6dxPnnAcyE/gIMf1oarvaQKzpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00125

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}