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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a5a9a4943495427a73da95f62f7daf1dd381338f6e5013b888acccadb3f790' 
  AND token = 'KOn4l1K1SKQPlU6SBe4nh455dTylt8RTGrrEcd0BAaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00119

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}