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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d78a2ebaddf757a20e7a76a7be2d60bb2645592a46698ec08e44c95081a776c' 
  AND token = '63QIi86mXPci14n2pM24xl0/YzJa+i20sDlo30TOVAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00114

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}