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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65bc2b7112a02a0c775639463b18b5ac3c8dc1c6d0b6d99038374cc22278c053' 
  AND token = 'DFLqzgzaczMkOkt2/4owmq/DML+IE9+fF1X2ZDwRVtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00117

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}