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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b6918fc928c92587025987c8adc461da43501d8f24d4b7aaa464f7aed443d4' 
  AND token = '18LnfD4WQb+6a/dhH5XQ5laFjBtTvoyEZFssXDZozJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}