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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b9e15f1f5bfce45b643c64b864857b531e1699aa69f4c2e477e4af515fb1f4' 
  AND token = 'Oq6/SfmdOyByk6H2nTTGoO/BXAiAC78H9T7T9RykvCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00117

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}