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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d508c3b81605eb1c83525c16799c0f465a8032c5fca902dcefc819050bfdf8a' 
  AND token = 'VAL9vBMz0w+TV4sgb9rzKlm9f7RfP3ZCeZ8E59Pr4Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00092

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}