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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d006f7c237918588bd92e2df9e8e226f33f3e512e53b5940c729c7226a2c62a' 
  AND token = 'R1/FQRt8sdk0iWU9Yju+EMzZgFR6OeCFSXcdAnU0WnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00098

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}