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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '212d8bcebb6d8b6c71ed2758a6b9ac5da0ec4c004a93274ee04d696ced369750' 
  AND token = 'I5nxdg7InnQ1C0whYTwRYGntp9NVlMyTqxoKX9WbvrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00106

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}