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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e24540fe831e5c9dd6f210a746d6cdb4bbf39c4370749ce009e1982cb63c07f' 
  AND token = 'QBFlZBkB2LEQ1xsDvopIDQXzVdbrio5WWRH7GxCU4bQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}