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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cba59b891c2d101de901db01bcce2edf9edc4a0074b6e9af52195525070e8ab' 
  AND token = 'uY1th2Pu+FJPGVNi7AEJh5tRMwk75c0sIZ25Qg9Cbns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}