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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f26835a0be043efecfc52deaf340db484bebafa5681acd6ff639b3abd95ad6f8' 
  AND token = '2EB0LgzF7AOmjpteCKz06UA0CFPWpVgvRmJ0t03SI0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}