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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae6e45d00d65c6137abbe10af1412cf0d7bd9e8cbffc6ffe7899c989031e881f' 
  AND token = 'wpifzRtMosB6RiSr/nv2A1VKo/sBVJlcqS2EVOYPR5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00110

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}