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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78404eeee3b96a02a19a38ae3bbb35d951dbe61710e42c3bd4a326f31cfc869e' 
  AND token = 'BxzriXRQNwKWcswI0XNWfPhmLNRENtgSOSctxudgVq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}