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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a641a379fd830e1f582f102f492eb8a50feffe75d67d9e2b2cbac8de59d7765' 
  AND token = 'cGRHW6Y560ODu3Gw9CE9YX0ZtbGPDhAyvXLWwb4sIjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00098

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}