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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ec86f601fce1d9082692c72b201fce8a800b28a7933bfde486bc33d0297b76' 
  AND token = 'pCOaM/cnG5XDdNjZ2LceU11uQxNKQssa+3JMlEtg41k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}