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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c386f0cc623abb366c1c577fe4cec865fe9db21b4a2e1deb8702defdae7ec815' 
  AND token = 'Iw6dJe4i2dLQHaTHLQXNJa4l6NfT2LKVoipTUSzNU6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00103

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}