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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a781651438e5e82c8e8e42467789fa41704913ed49249cf61aff3a2c5075218' 
  AND token = 'QuxSpBEfzr8N9qecwzprB+r5NPllu40xlZDbi2qKSc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00097

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}