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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3add66a0d5b9c6f865b48800e599f9f8109f42566a566020a872abe7e0ed2a7' 
  AND token = 'r1Pkm7L58TCZf/uKaM8PBHC2zYA6mGv3cBBBpq1AN1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00101

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}