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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '410f51911599caa0e6e2bef7dcf42db5e0d13b05211c4f224c6ee606645174e4' 
  AND token = '+sYOCljlQLciJajI8qRVSP1mD6O99zY+w1fHbYOOsPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00099

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}